S.E.M.I. – Side Effects May Include...

S.E.M.I. fosters strong teamwork and communication skills as players cooperate to escape a chaotic clinic. It challenges cognitive abilities through problem-solving, strategic thinking, and adapting to unpredictable events and abilities. The game also provides engaging motor skill development through combat and navigating dynamic environments.

The game features high levels of violence and frequent references to drug use as a core mechanic. Its chaotic and unpredictable nature, coupled with the theme of a mental hospital and 'madness,' could be unsettling. While cooperative, the game's design can lead to competitive toxicity among friends, and its variable reward system for abilities may encourage prolonged engagement.